WebJul 14, 2024 · Cluster randomised trials (CRTs) involve randomisation of groups (clusters) of individuals to control or intervention conditions. 1 The CRT design is commonly used to evaluate non-drug interventions, such as … Webno value to the design of a study. The investigator faces the choice of sample size as one of the first practical problems in designing an actual controlled trial. Similarly, in assessing the results of a published con-trolled trial, the critical reader looks to the sample size to help him or her interpret the relevance of the results. Other
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