WebJan 1, 2012 · expression profiling dataset. For the HSF1-binding data, a gene was associated with a. significant binding peak if the enriched peak fell within 2,000 or 10,000bp upstream or. WebHSF1 Gene. HSF1. The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. [provided by RefSeq, Jul 2008]
HSF1Base: A Comprehensive Database of HSF1 (Heat …
WebApr 25, 2008 · We then apply the method to a real world biological dataset by predicting heat shock-related DE genes from a Saccharomyces cerevisiae hsf1 mutant microarray … WebNov 13, 2006 · HSF1 1 Systematic Name YGL073W SGD ID SGD:S000003041 Aliases EXA3 31, MAS3 Feature Type ORF , Verified ... Referenced datasets may contain one … how big does a walnut tree grow
The EGFR-HSF1 axis accelerates the tumorigenesis of …
WebOct 16, 2024 · Collectively, these data suggest that in LSCs, HSF1 regulates a diverse functional array of genes, including mitochondrial metabolism, in addition to its classic role in the heat shock response.... WebDec 31, 2024 · First, we analyzed the differential mRNA expression of HSF1 gene across cancer datasets. As illustrated in Fig. 1A, the expression level of HSF1 mRNA was … WebJan 26, 2024 · HSF1 activation requires nuclear localization, trimerization, DNA binding, phosphorylation and gene transactivation. Phosphorylation at S326 is an important regulator of HSF1 transcriptional activity. Phosphorylation at S326 is mediated by AKT1, mTOR, p38, MEK1 and DYRK2. Here, we observed activation of HSF1 by AKT1 independently of mTOR. how big does a youtube thumbnail have to be