WebAn IFN-related DNA damage resistance signature (IRDS) correlates with resistance to adjuvant chemotherapy and with recurrence after radiotherapy in patients with breast cancer , suggesting that tumor cells overexpressing IRDS genes, including STAT1, ISG15, and IFIT1, as a result of chronic activation of the IFN signaling pathway might receive ... WebNov 2, 2024 · Platinum-based chemotherapy drugs are used to treat many types of cancer, including lung, breast, ovarian, and testicular cancer. Though effective, these drugs can cause many side effects.
University of Cincinnati Cancer Center presents research at AACR ...
WebApr 7, 2024 · It is well established that cancer is a disease of our genes. However, resistance to therapy might go beyond cancer mutations that usually alter the function of genes. It may not be new mutations ... WebMar 30, 2024 · Validation of a therapy that overcomes chemotherapy resistance in colon and rectal cancer. Graphical abstract. Credit: Journal of Medicinal Chemistry (2024). … rust day night cycle
Chemotherapy-resistant ovarian cancer cells protect their …
Web1 day ago · Recent studies have also focused on the relevance between MMR function and chemotherapy resistance. Either abnormal expression of or mutations in MMR genes … WebMar 3, 2024 · Certain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, according to a new study from University of Pittsburgh and UPMC ... WebMar 3, 2024 · The development of resistance to chemotherapy continues to be the major impediment in the treatment of cancer patients. Newer agents, whether chemotherapeutic or targeted, are constantly being developed. Though most anticancer therapies will alter tumor growth, in most cases the effect is not long lasting and treatment failure has an impact on ... schedule sign in sheet