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Alantolactone

WebAlantolactone (ALT), a natural sesquiterpene lactone, possesses antitumor properties in a number of cancer cell lines. In the present study, we investigated how ALT acts synergistically with oxaliplatin on human colorectal cancer HCT116 and RKO cells in … WebThen we identified alantolactone, a sesquiterpene lactone, could efficiently inhibit the promoter activity of TSP50 gene, further results revealed that alantolactone also efficiently inhibited the expression of TSP50 in both mRNA and protein levels. Moreover, we found alantolactone could increase the ratio of Bax/Bcl-2, and activate caspase-9 ...

Life Free Full-Text Alantolactone Suppresses Proliferation and the ...

WebThen we identified alantolactone, a sesquiterpene lactone, could efficiently inhibit the promoter activity of TSP50 gene, further results revealed that alantolactone also … WebNov 1, 2024 · Alantolactone exhibits selective antitumor effects in HELA human cervical cancer cells by inhibiting cell migration and invasion, G2/M cell cycle arrest, mitochondrial mediated apoptosis and... cynthia idavoy https://wearevini.com

Alantolactone = 98 HPLC 546-43-0

WebApr 1, 2024 · Alantolactone (ALT) is one of the most important STLs and it is derived from Inula helenium root (elecampane) in large amounts (Fig. 1). This plant grows in East Asia, Europe, and North America. Alantolactone has a variety of in vitro biochemical properties, including: • induces apoptosis and cell cycle arrest in lung squamous cancer cells • suppresses STAT3 activation • has antiinflammatory effects by inhibiting chemokine production and STAT1 phosphorylation billy\u0027s weekly liar newspaper

Discovery of alantolactone as a natural NLRP3 inhibitor to …

Category:Diversity Modification and Structure-Activity Relationships of Two ...

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Alantolactone

Alantolactone Alleviates Rise in Markers of Periodontitis by ...

WebFeb 23, 2024 · Alantolactone, a natural sesquiterpene lactone, exerts its antiallergic, antibacterial, antimicrobial, antifungal, anticancer, and neuroprotective effects by virtue of its anti-inflammatory and... WebDec 6, 2024 · Alantolactone (molecular weight = 232.31, Fig. 1 a), an allergenic sesquiterpene lactone, is mainly extracted from the roots of Inula helenium L. Alantolactone is a well known medicinal plant officially listed in some European pharmacopeias as elecampane (Stojakowska et al. 2006; Trendafilova et al. 2010 ).

Alantolactone

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WebAlantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal … WebElecampane is a soothing herb that has been used to treat coughs associated with bronchitis, asthma, and whooping cough. More. . is a demulcent (soothing herb) that has …

WebAug 27, 2024 · Alantolactone Inhibits Melanoma Cell Culture Viability and Migration and Promotes Apoptosis by Inhibiting Wnt/β-Catenin Signaling Bentham Science Login Register Cart 0 Home Publications Articles By Disease Marketing Opportunities For Librarians For Authors & Editors More Anti-Cancer Agents in Medicinal Chemistry Editor … Web2 days ago · Alantolactone treatment reduces TFEB expression in pancreatic cancer cells, which contributes to the lysosome dysfunction, autophagosome accumulation and the consequent induction of cell apoptosis .

WebJan 1, 2024 · Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the … WebAlantolactone (Alant camphor) is a sesquiterpene lactone; has potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway.

WebJan 20, 2024 · Alantolactone directly bound to the NACHT domain of NLRP3 to inhibit activation and assembly of NLRP3 inflammasomes. Molecular simulation analysis …

Webalantolactone: [noun] a white crystalline lactone C15H20O2 obtained from elecampane root. cynthia idWebJan 29, 2024 · In this work, two isolated STLs 1β-hydroxy alantolactone ( 1) and ivangustin ( 2) were derivatized through diversity-oriented strategy, and in vitro cytotoxic activity assessments were conducted... cynthia icenhourWebAlantolactone inhibits cell proliferation by interrupting the interaction between Cripto-1 and activinreceptor type II A in activin signaling pathway. J Biomol Screen 2011 Jun;16(5):525-35. (IF 2.297) 43. Ge S, Wang G, Shen Y, Zhang Q, Jia D, Wang H, Dong Q, Yin T. Cytotoxic effects of MgO nanoparticles on human umbilical vein endothelial cells ... cynthia ichiriu kellerWebApr 28, 2015 · Radix Inulae is endemic to China and has been used in traditional medicine to treat upper body pain, emesis and diarrhoea, and to eliminate parasites. Here, an UPLC-MS/MS method was developed and applied to study the pharmacokinetics, distribution and excretion of isoalantolactone and alantolactone, which are two main active … cynthia ickesWebAlantolactone C15H20O2 CID 72724 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … cynthia idletteWebApr 2, 2024 · Alantolactone, a sesquiterpene lactone, occurs as one of the major constituents of Inula helenium and Inula racemosa (Family: Asteraceae) (Gao et al. 2024; Seca et al. 2014 ). billy\u0027s western wear coupon codeWebDec 17, 2012 · Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-kappaB, MAPK and AP-1 via the … billy\u0027s well drilling beaufort sc